Genome Analysis, Metabolic Potential, and Predatory Capabilities of Herpetosiphon llansteffanense sp. nov.

Paul G. Livingstone ^[1] ; Russell M. Morphew ^[1] ; Alan R. Cookson ^[1] ; David E. Whitworth ^[1]
1. [1] Aberystwyth University
  
  Aberystwyth University
  
  Aberystwyth, Reino Unido
Localización: Applied and Environmental Microbiology, ISSN 0099-2240, Vol. 84, Nº 22, 2018
Idioma: inglés
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Resumen
- Predatory bacteria are able to kill and consume other microbes and are therefore of interest as potential sources of new antimicrobial substances for applications in the clinic. “Wolf pack” predators kill prey by secreting antimicrobial substances into their surroundings, and those substances can kill prey organisms independently of the predatory cells. The genus Herpetosiphon exhibits wolf pack predation, yet its members are poorly described compared to other wolf pack predators, such as the myxobacteria. By providing a thorough characterization of a novel Herpetosiphon species, including its predatory, biochemical, and genomic features, this study increases our understanding of genomic variation within the Herpetosiphon genus and how that variation affects predatory activity. This will facilitate future rational exploitation of genus members (and other wolf pack predators) as sources of novel antimicrobials.