Work-Related Stressors and Increased Risk of Benzodiazepine Long-Term Use: Findings From the CONSTANCES Population-Based Cohort

• Autores: Guillaume Airagnes, Cédric Lemogne, Romain Olekhnovitch, Yves Roquelaure, Nicolas Hoertel, Marcel Goldberg, Frédéric Limosin, Marie Zins
• Localización: American journal of public health, ISSN 0090-0036, Vol. 109, Nº. 1, 2019, págs. 119-125
• Idioma: inglés
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• Resumen

  • Objectives. To examine whether stressful job exposure to the public could be associated with having long-term benzodiazepine use.Methods. From the participants included between 2012 and 2016 in the French population-based CONSTANCES cohort, 13?934 men and 19?261 women declared a daily job exposure to the public and rated the frequency of stressful exposure. We examined benzodiazepine long-term use by using drug reimbursement administrative registries. Logistic regressions provided odds ratios (ORs) of benzodiazepine long-term use, with stratification for gender and adjustment for age, education, and area deprivation index. Occupational grade, job strain, depression, self-rated health, and alcohol use disorder were additional stratification variables.Results. Benzodiazepine long-term use was positively associated with stressful exposure to the public (?often or always? vs ?rarely or never?) in men (OR?=?2.2; 95% confidence interval [CI]?=?1.8, 2.8) and women (OR?=?1.6; 95% CI?=?1.4, 1.9), with dose-dependent relationships (P trends?