Metastatic anaplastic oligodendroglioma

• Autores: Ana Sofia Patrão, Maria Inês Sequeira, Manuel Jácome, Joaquina Maurício
• Localización: Galicia Clínica, ISSN 0304-4866, ISSN-e 1989-3922, Vol. 79, Nº. 4 (Diciembre), 2018, págs. 127-129
• Idioma: inglés
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• Resumen

  • Metastization from a brain primary tumor is a rare event. The mechanisms of metastization and the best treatment approach are still unknown.

    Knowledge is, so far, mostly based on case reports.

    We report a case of a patient with the diagnosis of an anaplastic oligodendroglioma, presenting, 9 months after the brain surgery, with spinal cord compression and pleural effusion. The patient underwent surgery for decompression and local radiotherapy to D12-L5, 30 Gy, 10 fractions and the histology confirmed metastasis of oligodendroglioma. Citology of pleural liquid confirmed the same origin. The patient started temozolomide with good clinical response and stabilization of the disease for 9 months.

    This is an uncommon case of bone and pleural metastization of anaplastic oligodendroglioma that had a good response to temozolomide in the metastatic setting.