(IR)Factor for NAIP Expression

• Autores: Sivapriya Kailasan Vanaja, Vijay A.K. Rathinam
• Localización: Cell, ISSN 0092-8674, Vol. 173, Nº. 4, 2018, págs. 817-818
• Idioma: inglés
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• Resumen

  • IRF8 is a master transcription factor for immune cell development. In this issue, Karki et al. reveal that IRF8 governs the constitutive expression of genes encoding for NAIP proteins that are critical for the innate immune sensing of bacteria.