Influence of a pharmaceutical intervention program on the use of potentially inappropriate medications in elderly patients
- Autores: José Manuel Caro Teller, Sara Ortiz Pérez, Marta González Sevilla, Mª Jesús Jiménez Cerezo, Carlos González Gómez, José Miguel Ferrari Piquero
- Localización: European journal of clinical pharmacy: atención farmacéutica, ISSN 2385-409X, Vol. 20, Nº. 4, 2018, págs. 197-203
- Idioma: inglés
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Resumen
Objective: To estimate the prevalence of potentially inappropriate medications (PIM) in the elderly population hospitalized in a third level hospital. The secondary objectives are to determine the degree of acceptance of the carried out pharmaceutical interventions, and to estimate how they affect the deprescribing of PIM at discharge. Method: Prospective unicentric study of intervention between November 2015 and March 2017. It included all the patients that were older than 74 years, with one or more PIM in their treatment. Results: The study included 5,416 patients, with 27.1% of them having one or more PIM prescribed (1,540). The mean age was 82.71 ±5.31 years (53.9% women). The 60.3% of the prescriptions were intervened, and the 41.3% of them were accepted by the physician responsible of the patient. 70.6% of the intervened PIM (655) were part of the domiciliary treatment of the patient. Interventions that involved a reduction in the dose of the drug had a higher acceptance rate (508; 47%) than those that implied a suspension or therapeutic substitution (143; 34%), with a statistically significant difference (Pearson χ2 = 16.52; p <0.001). The relationship between the acceptance of the pharmaceutical interventions and the type of prescribing service (clinical physicians vs surgeons) was not statistically significant (Pearson χ2 = 3.27; p = 0.07). In 30.7% of cases the PIM were deprescribed at discharge. Conclusions: The inclusion of a pharmacotherapy follow-up program in the hospital setting promotes a change of attitude regarding the prescription of these drugs
