Using metagenomics to characterize an expanding virosphere

• Autores: Yong-Zhen Zhang, Mang Shi, Edward C. Holmes
• Localización: Cell, ISSN 0092-8674, Vol. 172, Nº. 6, 2018 (Ejemplar dedicado a: The Microbial Word), págs. 1168-1172
• Idioma: inglés
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• Resumen

  • We know less about viruses than any other lifeform. Fortunately, metagenomics has led to a massive expansion in the known diversity of the virosphere. Here, we discuss how metagenomics has changed our understanding of RNA viruses and present some of the remaining challenges, including characterization of the “dark matter” of divergent viral genomes.