A virus found in sewage has spawned a drug that targets plaques implicated in a host of brain-crippling conditions, including Alzheimer's, Parkinson's and Creutzfeldt-Jakob disease. Results from tests of the drug show that it breaks up plaques in mice affected with the equivalent of Alzheimer's or Parkinson's, and improves their memories and cognitive abilities. Other promising results in rats and monkeys mean that the drug's developers, NeuroPhage Pharmaceuticals in Cambridge, are poised to apply for permission to start testing it in people, with trials staffing as early as next year
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