Hiv’s achille´s heel.

• Autores: Rogier W. Sanders, Ian A. Wilson, John P. Moore
• Localización: Scientific American, ISSN 0036-8733, Vol. 315, Nº. 6, 2016, págs. 50-55
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • The article focuses on research into a vaccine for the HIV virus. It comments on the difficulty of developing antibodies that prevent the HIV virus from attaching to CD4+ proteins and CCR5 proteins to infect CD4+ T cells and the problem with the virus envelope protein falling apart when separated from an intact virus. It mentions the use of artificial trimers which mimic Env proteins and can be redesigned to develop a protective vaccine.