Novel Functional Imaging of Neuroendocrine Tumors Anders Sundin, MD, PhD INTRODUCTION Imaging of neuroendocrine tumors (NETs) is based on the combination of morphologic (radiologic) and functional (nuclear medicine) techniques because they provide com- plementary information ( Box 1 ). Functional imaging with modern scanners can currently be performed as hybrid imaging procedures, whereby PET and single photon emission computed tomography (SPECT) are performed together with computed to- mography (CT) scan as PET/CT scan and SPECT/CT scanning, and in recent years also PET/MRI. Hybrid procedures generally achieve a better imaging yield, as compared with separate interpretation of morphologic and functional imaging, and additionally improve reader confidence. Because conventional radiologic cross- sectional methods (CT scanning and MRI) constitute the basis for NET imaging and because the quality of both components is crucial for the result of hybrid imaging (PET/CT scanning and PET/MRI), this article concentrates on the functional
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