CSR-1 slices a balance

• Autores: Ruby Yu, Danesh Moazed
• Localización: Cell, ISSN 0092-8674, Vol. 165, Nº. 2, 2016, págs. 267-269
• Idioma: inglés
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• Resumen

  • CSR-1 is a germline-expressed C. elegans Argonaute protein essential for viability. In this issue of Cell, Gerson-Gurwitz et al. now demonstrate a role for CSR-1 and its slicer activity in downregulating the levels of maternally deposited mRNAs to fine-tune the expression of proteins with critical roles in embryonic cell divisions.