Insulin signaling in a bit of a jam

• Autores: Vassily I. Kutyavin, Ajay Chawla
• Localización: Cell, ISSN 0092-8674, Vol. 165, Nº. 2, 2016, págs. 264-265
• Idioma: inglés
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• Resumen

  • In this issue of Cell, Okin and Medzhitov report that sustained inflammation promotes hyperglycemia by targeting the mevalonate pathway. This represents an important step forward in understanding the mechanisms underlying the association between chronic low-grade inflammation and disruption of normal tissue functions in metabolic diseases.