Drug could be the first to reverse type 2 diabetes

• Autores: Andy Coghlan
• Localización: New scientist, ISSN 0262-4079, Nº. 3119, 2017, pág. 11
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • A daily drug can reverse diabetes in mice, opening up the possibility of an easier way for diabetics to keep their blood sugar level within safe limits. Stephanie Stanfordat the University of California, San Diego, and her team have developed an oral drug that can restore the ability of diabetic mice to control their blood sugar levels. The drug works by inhibiting an enzyme called low molecular weight protein tyrosine phosphatase (LMPTP), which seems to contribute to cells losing their sensitivity to insulin. By hindering LMPTP, the drug reawakens insulin receptors on the surface of cells--especially in the liver--which normally absorb excess sugar from the blood when they detect insulin.