Control of the development of limb musculature

• Autores: Marc Rodríguez-Niedenführ
• Localización: European Journal of anatomy, ISSN-e 1136-4890, Vol. 15, Nº. 1, 2011, págs. 3-9
• Idioma: inglés
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• Resumen

  • Limb muscle development is an embryonic multistep process including paraxial mesoderm segmentation, somite compartmentalisation, muscle precursor cell delamination (epithelial-mesenchymal transition), proliferation-migration and, finally, terminal differentiation. Classical as well as the latest research articles in this developmental biology field are reviewed and discussed. A general overview of molecular mechanisms controlling muscle development in the limb of the developing embryo is presented.