Evidence that Parkinson's disease may be an autoimmune disorder could lead to new ways to treat the illness. Parkinson's begins with abnormal clumping of a protein called synuclein in the brain. Neighboring dopamine-producing neurons then die, causing tremors and difficulty moving. The prevailing wisdom has been that these neurons die from a toxic reaction to synuclein deposits. However. Parkinson's has been linked to some gene variants that affect how the immune system works, leading to an alternative theory that synuclein causes Parkinson's by triggering the immune system to attack the brain
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