Dissimilar Symmetric Word Pairs in the Human Genome

• Autores: Ana Tavares, Jakob Raymaekers, Peter J. Rousseeuw, Raquel M. Silva, Carlos A.C. Bastos, Armando Pinho, Paula Brito, Vera Afreixo
• Localización: 11th International Conference on Practical Applications of Computational Biology & Bioinformatics / Florentino Fernández Riverola (ed. lit.), 2017, ISBN 978-3-319-60815-0, págs. 248-256
• Idioma: inglés
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• Resumen

  • In this work we explore the dissimilarity between symmetric word pairs, by comparing the inter-word distance distribution of a word to that of its reversed complement. We propose a new measure of dissimilarity between such distributions. Since symmetric pairs with different patterns could point to evolutionary features, we search for the pairs with the most dissimilar behaviour. We focus our study on the complete human genome and its repeat-masked version.