Coronally advanced flap and connective tissue graft with or without plasma rich in growth factors (PRGF) in treatment of gingival recession

• Niloofar Jenabian ^[1] ; Mina Motallebnejad ^[1] ; Ehsan Zahedi ^[2] ; Nima D. Sarmast ^[3] ; Nikola Angelov ^[3]
  1. [1] Babol University of Medical Sciences

     Babol University of Medical Sciences

     Irán

     
  2. [2] University of California Los Angeles

     University of California Los Angeles

     Estados Unidos

     
  3. [3] Department of Periodontics and Dental Hygiene, The University of Texas School of Dentistry at Houston, Houston, Texas, USA

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• Localización: Journal of Clinical and Experimental Dentistry, ISSN-e 1989-5488, Vol. 10, Nº. 5 (May ), 2018, págs. 431-438
• Idioma: inglés
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• Resumen

  • Several researchers have tried to improve the results of gingival recession treatment techniques. One of the methods is to use growth factors The present study was undertaken to evaluate the effect of CAF (coronally advanced flap) + CTG (connective tissue graft) + PRGF (plasma rich in growth factors) in the treatment of Miller Class I buccal gingival recession.

    Twenty-two teeth with Miller Class I gingival recession in 6 patients 26 ‒ 47 years of age were included in a split-mouth designed randomized controlled trial (RCT). In each patient, one side was treated with CAF + CTG + PRGF (test) and the other side was treated with CAF + CTG (control). The following parameters were measured before surgery and up to 6 months after surgery on the mid-buccal surface of the tooth: keratinized tissue width (KTW), clinical attachment level (CAL), probing depth (PD), vertical recession depth (VRD), recession depth (RD), gingival thickness (GT), root coverage in percentage (RC%) and the distance between the CEJ and mucogingival junction (MGJL). Data were analyzed with paired t-test and repeated measures ANOVA.

    After 6 months noticeable improvements were observed in both groups in all the variables measured except for PD; however, the differences between the two groups were not significant. RC% was 80 ± 25% and 67 ± 28% in the test and control groups, respectively, after 6 months.

    Both CAF + CTG + PRGF and CAF + CTG treatment modalities resulted in favorable root coverage; however, the addition of PRGF added no measurable significant effect.