Opening a Chromatin Gate to Metastasis

• Autores: John D. Minna, Jane E. Johnson
• Localización: Cell, ISSN 0092-8674, Vol. 166, Nº. 2, 2016, págs. 275-276
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • What changes need to occur in a primary tumor to make it metastatic? Denny et al. address this question for small cell lung cancer (SCLC), finding that changes in genomic accessibility mediated by a single transcription factor, NFIB, comprise at least one mechanism influencing metastasis.