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A pragmatic evidence-based clinical management algorithm for burning mouth syndrome

    1. [1] Loma Linda University Medical Center

      Loma Linda University Medical Center

      Estados Unidos

    2. [2] BS, Loma Linda University School of Medicine, Loma Linda, CA, USA
  • Localización: Journal of Clinical and Experimental Dentistry, ISSN-e 1989-5488, Vol. 10, Nº. 4 (April ), 2018, págs. 321-326
  • Idioma: inglés
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  • Resumen
    • Burning mouth syndrome is a poorly understood disease process with no current standard of treatment. The goal of this article is to provide an evidence-based, practical, clinical algorithm as a guideline for the treatment of burning mouth syndrome.

      Using available evidence and clinical experience, a multi-step management algorithm was developed. A retrospective cohort study was then performed, following STROBE statement guidelines, comparing outcomes of patients who were managed using the algorithm and those who were managed without.

      Forty-seven patients were included in the study, with 21 (45%) managed using the algorithm and 26 (55%) managed without. The mean age overall was 60.4 ±16.5 years, and most patients (39, 83%) were female. Cohorts showed no statistical difference in age, sex, overall follow-up time, dysgeusia, geographic tongue, or psychiatric disorder; xerostomia, however, was significantly different, skewed toward the algorithm group. Significantly more non-algorithm patients did not continue care (69% vs. 29%, p=0.001). The odds ratio of not continuing care for the non-algorithm group compared to the algorithm group was 5.6 [1.6, 19.8]. Improvement in pain was significantly more likely in the algorithm group (p=0.001), with an odds ratio of 27.5 [3.1, 242.0].

      We present a basic clinical management algorithm for burning mouth syndrome which may increase the likelihood of pain improvement and patient follow-up.


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