Legionella Effectors Explored with INSeq: New Functional Insights

• Autores: Monica Rolando, Carmen Buchrieser
• Localización: Trends in microbiology, ISSN 0966-842X, Vol. 26, Nº. 3, 2018, págs. 169-170
• Idioma: inglés
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• Resumen

  • Legionella pneumophila secretes over 300 effector proteins that manipulate host cells. This multiplicity of effectors hampers the characterization of their individual roles. Shames et al. report a new approach to solve the enigma of Legionella effector function by using INSeq to analyse effector functions in the context of infection.