Improving Vaccine and Immunotherapy Design Using Biomaterials

• Autores: Michelle L. Bookstaver, Shannon J. Tsai, Jonathan S. Bromberg, Christopher M. Jewell
• Localización: Trends in immunology, ISSN 1471-4906, Vol. 39, Nº. 2, 2018, págs. 135-150
• Idioma: inglés
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• Resumen

  • Polymers, lipids, scaffolds, microneedles, and other biomaterials are rapidly emerging as technologies to improve the efficacy of vaccines against infectious disease and immunotherapies for cancer, autoimmunity, and transplantation. New studies are also providing insight into the interactions between these materials and the immune system. This insight can be exploited for more efficient design of vaccines and immunotherapies. Here, we describe recent advances made possible through the unique features of biomaterials, as well as the important questions for further study.