Protein Kinase CK2: An Emerging Regulator of Immunity

• Autores: Sara A. Gibson, Etty N. Benveniste
• Localización: Trends in immunology, ISSN 1471-4906, Vol. 39, Nº. 2, 2018, págs. 82-85
• Idioma: inglés
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• Resumen

  • Although it has historically been studied in the context of cancer, recent literature has highlighted the importance of the highly conserved serine/threonine kinase casein kinase II (CK2) in inflammatory disorders. Most strikingly, CK2 is a major regulator of the Th17–Treg axis relevant to many T cell-driven autoimmune disorders including multiple sclerosis (MS).