Does atopy affect the course of viral pneumonia?

• S.B. Erdem ^[8] ; D. Can ^[8] ; S. Girit ^[9] ; F. Çatal ^[1] ; V.Şen ^[2] ; S.Pekcan ^[3] ; H.Yüksel ^[4] ; A.Bingöl ^[5] ; I.Bostancı ^[10] ; D.Erge ^[6] ; R. Ersu ^[7]
  1. [1] Inonu University

     Inonu University

     Turquía

     
  2. [2] Dicle University

     Dicle University

     Turquía

     
  3. [3] Necmettin Erbakan University

     Necmettin Erbakan University

     Turquía

     
  4. [4] Celal Bayar University

     Celal Bayar University

     Turquía

     
  5. [5] Akdeniz University

     Akdeniz University

     Turquía

     
  6. [6] Adnan Menderes University

     Adnan Menderes University

     Turquía

     
  7. [7] Marmara University

     Marmara University

     Turquía

     
  8. [8] Dr Behcet Uz Children's Hospital, Turkey
  9. [9] Kartal Dr Lütfü Kırdar Training and Research Hospital, Turkey
  10. [10] Dr. Sami Ulus Obstetrics and Child Health and Diseases Training and Research Hospital. Ankara, Turkey

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• Localización: Allergologia et immunopathologia: International journal for clinical and investigate allergology and clinical immunology, ISSN-e 1578-1267, ISSN 0301-0546, Vol. 46, Nº. 2, 2018, págs. 119-126
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Background The presence of atopy is considered as a risk factor for severe respiratory symptoms in children. The objective of this study was to examine the effect of atopy on the course of disease in children hospitalised with viral pneumonia.

    Methods Children between the ages of 1 and 6 years hospitalised due to viral pneumonia between the years of 2013 and 2016 were included to this multicentre study. Patients were classified into two groups as mild–moderate and severe according to the course of pneumonia. Presence of atopy was evaluated with skin prick tests. Groups were compared to evaluate the risk factors associated with severe viral pneumonia.

    Results A total of 280 patients from nine centres were included in the study. Of these patients, 163 (58.2%) were male. Respiratory syncytial virus (29.7%), Influenza A (20.5%), rhinovirus (18.9%), adenovirus (10%), human metapneumovirus (8%), parainfluenza (5.2%), coronavirus (6%), and bocavirus (1.6%) were isolated from respiratory samples. Eighty-five (30.4%) children had severe pneumonia. Atopic sensitisation was found in 21.4% of the patients. Ever wheezing (RR: 1.6, 95% CI: 1.1–2.4), parental asthma (RR: 1.5, 95% CI: 1.1–2.2), other allergic diseases in the family (RR: 1.8, 95% CI: 1.2–2.9) and environmental tobacco smoke (RR: 1.6, 95% CI: 1.1–3.5) were more common in the severe pneumonia group.

    Conclusions When patients with mild–moderate pneumonia were compared to patients with severe pneumonia, frequency of atopy was not different between the two groups. However, parental asthma, ever wheezing and environmental tobacco smoke exposure are risk factors for severe viral pneumonia in children.