Posterior polymorphous dystrophy and keratoconus: more than a casual association?

• Autores: Luis F. Mejía, Diego Aristizábal Montes, Juan M. Palacio, Natalia L. Calle
• Localización: Journal of Emmetropia: Journal of Cataract, Refractive and Corneal Surgery, ISSN-e 2171-4703, Vol. 2, Nº. 3, 2011, págs. 115-119
• Idioma: inglés
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• Resumen

  • PURPOSE: To report the simultaneous presentation of Posterior Polymorphous Corneal Dystrophy and Keratoconus in a group of patients from the Cornea and External Diseases Clinic at CES University, between 1995 and 2008 and provide a plausible explanation for it.

    METHODS: This is a retrospective clinical records review of patients with simultaneous presentation of Posterior Polymorphous Corneal Dystrophy and Keratoconus who had undergone a complete ophthalmological examination; the diagnosis of Posterior Polymorphous Corneal Dystrophy was based on clinical findings on slit lamp examination and the diagnosis of Keratoconus was confirmed by corneal topography.

    RESULTS: We identified five patients with a simultaneous clinical presentation of Posterior Polymorphous Corneal Dystrophy and Keratoconus.

    CONCLUSIONS: Weighing the facts, there is a possible association between Posterior Polymorphous Corneal Dystrophy and Keratoconus well beyond simple chance, explained on the basis of a common embryological origin together with simultaneous chromosomal alterations, justifying their simultaneous presentation.