Congenital Hypopituitarism

• Autores: John S. Parks
• Localización: Clinics in Perinatology, ISSN 0095-5108, Vol. 45, Nº. 1, 2018, págs. 75-91
• Idioma: inglés
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• Resumen

  • Mutations of growth hormone genes and pituitary transcription factors account for a small proportion of cases of severe congenital hypopituitarism. Most cases show characteristic MRI findings of pituitary stalk interruption syndrome. Clinical suspicion should prompt assessment of cortisol, free T4, thyroid-stimulating hormone, and growth hormone levels together with MRI of the hypothalamic and pituitary regions.