Risky business: the circuits that impact stress-induced decision-making

• Autores: A. F. T. Arnsten, Daeyeol Lee, Christopher Pittenger
• Localización: Cell, ISSN 0092-8674, Vol. 171, Nº. 5, 2017, págs. 992-993
• Idioma: inglés
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• Resumen

  • How does stress promote risky decision-making? Friedman et al. find that stress disrupts inhibition of striatal circuits by prefrontal cortex, rendering animals insensitive to potential losses. This may help explain how stress contributes to substance abuse and how it can disinhibit automatic behaviors, such as tics in Tourette syndrome.