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Resumen de Bilateral acute depigmentation of the iris. First report on the american continent and 5 years follow-up of two patients

Francisco Barraquer, Luis F. Mejía

  • PURPOSE: To report the !rst cases of Bilateral Acute Depigmentation of the Iris (BADI) in the American continent, the !rst iris angiography of one such case, and a follow-up of two cases over several years.

    METHODS: Two patients were diagnosed in a routine eye exam, and two others were retrieved from our photo archives, called for an appointment and re-examined. One patient underwent iris angiography.

    RESULTS: Two male and two female patients were diagnosed, with a median age of 47 yrs (range 16 to 75). Only one patient recalled having had an episode of bilateral red eye during the past year. All but one had bilateral asymmetrical depigmentation of the iris stroma, extending from the iris root but not reaching the pupillary border, normal pupillary function, no transillumination defects and no anterior chamber cellularity or $are;

    intraocular pressure was normal in all patients. Iris angiography was normal showing a window defect where the iris atrophy was present. In the 2 patients with years of follow-up, the depigmented iris became only partially re-pigmented and re-thickened.

    CONCLUSION: Patients with BADI syndrome have bilateral, asymmetrical depigmentation of the iris stroma, without transillumination or pupillary deformities. "e depigmentation and anterior stromal atrophy cedes partially over time. No etiology has been established.


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