Resumen de SEOM clinical guideline on unknown primary cancer (2017)

Fernando Losa Gaspà, Gema Soler González, Antonio Casado Herráez, Anna Estival González, I. Fernández Pérez, S. Giménez, Federico Longo Muñoz, Roberto Pazo Cid, J. Salgado, Miguel Ángel Seguí Palmer

• Cancer of unknown primary site is a histologically confirmed cancer that manifests in advanced stage, with no identifiable primary site following standard diagnostic procedures. Patients are initially categorized based on the findings of the initial biopsy: adenocarcinoma, squamous-cell carcinoma, neuroendocrine carcinoma, and poorly differentiated carcinoma. Appropriate patient management requires understanding several clinical and pathological features that aid in identifying several subsets of patients with more responsive tumors.