Planning for remodelling: nuclear architecture, chromatin and chromosomes

• Autores: J.S. (Pat) Heslop-Harrison
• Localización: Trends in plant science, ISSN 1360-1385, Vol. 8, Nº. 5, 2003, págs. 195-197
• Idioma: inglés
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• Resumen

  • DNA sequences occupy three-dimensional positions and their architecture is related to gene expression, gene–protein interactions and epigenetic processes. The recent analysis of chromosome 4 in Arabidopsis interphase nuclei reveals that gene-rich, undermethylated DNA is composed of active loops of 200 to 2000 kb associated with acetylated histones, providing a well-defined model system to study chromatin in its nuclear context.