Resumen de Oral supplements to improve lactose digestion and tolerance
There are two principal microbial sources of β-galactosidase (lactase): (i) yeast (Kluyveromyces lactis) and (ii) fungi (Aspergillus niger and A. oryzae). From these sources, several over-the-counter lactase supplements have been prepared and introduced into the US market. Controlled clinical trials have shown that these lactose digestive aids are effective. However, the results have been vari able. A consistent observation in many of these is that there may be a subpopulation with very low levels of endogenous residual lactase. These people might need much higher levels of oral supplements than currently recommended. Generally, the products are expensive and research should be directed toward reducing the cost of these oral supplements.
