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Global Sensory Impairment Predicts Morbidity and Mortality in Older U.S. Adults

  • Autores: Jayant M. Pinto, Kristen Wroblewski, Megan Huisingh Scheetz, Camil Correia, Kevin J. Lopez, Rachel C. Chen, David W. Kern, Philip L. Schumm, William Dale, Martha K. McClintock
  • Localización: Journal of the American Geriatrics Society, ISSN 0002-8614, Vol. 65, Nº. 12, 2017, págs. 2587-2595
  • Idioma: inglés
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  • Resumen
    • Objectives:

      To evaluate global sensory impairment (GSI, an integrated measure of sensory dysfunction) as a predictor of physical function, cognition, overall health, and mortality.

      Design:

      Prospective study.

      Setting The National Social Life, Health, and Aging Project.

      Participants:

      A national probability sample of 3,005 home-dwelling older U.S. adults assessed at baseline (2005–06) and 5-year follow-up (2010–11).

      Measurements:

      Gait speed, activity, disability, cognition, overall health, 5-year mortality.

      Results:

      At baseline, older adults with worse GSI were slower (Timed Up and Go times: odds ratio (OR) = 1.32, 95% confidence interval (CI) = 1.17–1.50) and had more activity of daily living deficits (≥2: OR = 1.26, 95% CI = 1.10–1.46). Five years later, they were still slower (timed walk: OR = 1.22, 95% CI = 1.05–1.42), had more disabilities (≥2 instrumental activities of daily living; OR = 1.45, 95% CI = 1.23–1.70), were less active (daytime activity according to accelerometry: β = −2.7, 95% CI = −5.2 to −0.2), had worse cognitive function (Montreal Cognitive Assessment; β = −0.64, 95% CI = −0.84 to −0.44), more likely to have poorer overall health (OR = 1.16, 95% CI = 1.03–1.31) and lose weight (>10%: OR = 1.31, 95% CI = 1.04–1.64), and have died (OR = 1.45, 95% CI = 1.19–1.76). All analyses were adjusted for relevant confounders at baseline, including age, sex, race and ethnicity, education, smoking, problem drinking, body mass index, comorbidities, and cognitive function.

      Conclusion:

      GSI predicts impaired physical function, cognitive dysfunction, significant weight loss, and mortality 5 years later in older U.S. adults. Multisensory evaluation may identify vulnerable individuals, offering the opportunity for early intervention to mitigate adverse outcomes.


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