Cancer evolution constrained by the immune microenvironment

• Autores: Nicholas McGranahan, Charles Swanton
• Localización: Cell, ISSN 0092-8674, Vol. 170, Nº. 5, 2017, págs. 825-827
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Tumor development is a Darwinian evolutionary process, involving the interplay between cancer subclones and the local immune microenvironment. These complex interactions are highlighted in this issue of Cell by the results from Jiménez-Sánchez et al. of a deep analysis of one patient with advanced serous carcinoma of the ovary.