Hyperbilirubinemia in Preterm Neonates

• Autores: Vinod K. Bhutani, Ronald J. Wong , David K. Stevenson
• Localización: Clinics in Perinatology, ISSN 0095-5108, Vol. 43, Nº. 2, 2016, págs. 215-232
• Idioma: inglés
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• Resumen

  • Preterm neonates with increased bilirubin production loads are more likely to sustain adverse outcomes due to either neurotoxicity or overtreatment with phototherapy and/or exchange transfusion. Clinicians should rely on expert consensus opinions to guide timely and effective interventions until there is better evidence to refine bilirubin-induced neurologic dysfunction or benefits of bilirubin. In this article, we review the evolving evidence for bilirubin-induced brain injury in preterm infants and highlight the clinical approaches that minimize the risk of bilirubin neurotoxicity.