Arrhythmogenic Right Ventricular Cardiomyopathy in the Boxer Dog: An Update

• Autores: Kathryn M. Meurs
• Localización: Veterinary Clinics of North America: Small Animal Practice: Small Animal Practice, ISSN-e 0195-5616, Vol. 47, Nº. 5, 2017, págs. 1103-1111
• Idioma: inglés
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• Resumen

  • Boxer arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited myocardial disease resulting in ventricular arrhythmias, syncope, and sometimes sudden death; a small number of cases develop left ventricular myocardial dysfunction.

    Familial boxer ARVC has been associated with a deletion in the striatin gene in many families of boxers. Boxers that are homozygous (two copies) for the deletion seem to have more severe disease.

    Treatment is directed to management of the arrhythmia and sotalol and/or mexiletine are the most commonly prescribed antiarrhythmics.

    Although some affected boxers die of sudden death or develop congestive heart failure, many of them develop ventricular arrhythmias and still live a normal lifespan.