Vitamin D Metabolism in Bariatric Surgery

• Autores: Marlene Chakhtoura, Maya Rahme, Ghada El-Hajj Fuleihan
• Localización: Endocrinology and metabolism clinics of North America, ISSN 0889-8529, Vol. 46, Nº. 4, 2017 (Ejemplar dedicado a: Vitamin D), págs. 947-982
• Idioma: inglés
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• Resumen

  • Hypovitaminosis D is common in obese patients and persists after roux-en-Y gastric bypass and sleeve gastrectomy. Several societies recommend screening for vitamin D deficiency before bariatric surgery, and replacement doses of 3000 IU/d and up to 50,000 IU 1 to 3 times per week, in case of deficiency, with periodic monitoring. These regimens are mostly based on expert opinion. Large trials are needed to assess the vitamin D dose response, by type of bariatric surgery, and evaluate the effect on surrogate markers of skeletal outcomes. Such data are essential to derive desirable vitamin D levels in this population.