Oral immunotherapy for food allergy: A Spanish guideline. Immunotherapy egg and milk Spanish guide (items guide). Part I: Cow milk and egg oral immunotherapy: Introduction, methodology, rationale, current state, indications contraindications and oral immunotherapy build-up phase

• A. Martorell ^[9] ; E. Alonso ^[10] ; L. Echeverría ^[3] ; C. Escudero ^[20] ; R. García-Rodríguez ^[11] ; C. Blasco ^[1] ; J. Bone ^[2] ; J. Borja-Segade ^[11] ; T. Bracamonte ^[3] ; A. Claver ^[12] ; J.L. Corzo ^[13] ; B. De la Hoz ^[4] ; R. Del Olmo ^[14] ; O. Dominguez ^[15] ; V. Fuentes-Aparicio ^[5] ; I. Guallar ^[2] ; H. Larramona ^[16] ; F. Martín-Muñoz ^[17] ; V. Matheu ; A. Michavila ^[18] ; I. Ojeda ^[19] ; P. Ojeda ^[19] ; M. Piquer ^[15] ; P. Poza ; M. Reche ^[6] ; P. Rodríguez del Río ^[20] ; M. Rodríguez ^[21] ; F. Ruano ^[7] ; S. Sánchez-García ^[20] ; S. Terrados ^[4] ; L. Valdesoiro ^[16] ; M. Vazquez-Ortiz ^[8]
  1. [1] Hospital Vall d'Hebron

     Hospital Vall d'Hebron

     Barcelona, España

     
  2. [2] Hospital Miguel Servet

     Hospital Miguel Servet

     Zaragoza, España

     
  3. [3] Hospital Severo Ochoa

     Hospital Severo Ochoa

     Madrid, España

     
  4. [4] Hospital Ramón y Cajal

     Hospital Ramón y Cajal

     Madrid, España

     
  5. [5] Hospital Clínico San Carlos de Madrid

     Hospital Clínico San Carlos de Madrid

     Madrid, España

     
  6. [6] Hospital Infanta Sofia

     Hospital Infanta Sofia

     Madrid, España

     
  7. [7] Hospital Infanta Leonor

     Hospital Infanta Leonor

     Madrid, España

     
  8. [8] Imperial College London

     Imperial College London

     Reino Unido

     
  9. [9] Hospital General Universitario de Valencia

     Hospital General Universitario de Valencia

     Valencia, España

     
  10. [10] Hospital General Universitario Gregorio Marañón

      Hospital General Universitario Gregorio Marañón

      Madrid, España

      
  11. [11] Hospital General Universitario Ciudad Real, España
  12. [12] Hospital Universitario Quirón Dexeus, España
  13. [13] Hospital Universitario Carlos Haya, España
  14. [14] Hospital Universitario Móstoles, España
  15. [15] Hospital San Joan de Deu, España
  16. [16] Hospital Universitario Parc Taulí, España
  17. [17] Hospital Infantil La Paz, España
  18. [18] Hospital General Castellón, España
  19. [19] Clínica Ojeda, Madrid, España
  20. [20] Hospital Universitario Infantil Niño Jesús, España
  21. [21] Hospital Fundación Alcorcón, España

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• Localización: Allergologia et immunopathologia: International journal for clinical and investigate allergology and clinical immunology, ISSN-e 1578-1267, ISSN 0301-0546, Vol. 45, Nº. 4, 2017, págs. 393-404
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Introduction Cow's milk and egg are the most frequent causes of food allergy in the first years of life. Treatments such as oral immunotherapy (OIT) have been investigated as an alternative to avoidance diets. No clinical practice guides on the management of OIT with milk and egg are currently available.

    Objectives To develop a clinical guide on OIT based on the available scientific evidence and the opinions of experts.

    Methods A review was made of studies published in the period between 1984 and June 2016, Doctoral Theses published in Spain, and summaries of communications at congresses (SEAIC, SEICAP, EAACI, AAAAI), with evaluation of the opinion consensus established by a group of experts pertaining to the scientific societies SEICAP and SEAIC.

    Results Recommendations have been established regarding the indications, requirements and practical aspects of the different phases of OIT, as well as special protocols for patients at high risk of suffering adverse reactions.

    Conclusions A clinical practice guide is presented for the management of OIT with milk and egg, based on the opinion consensus of Spanish experts.