Physiological expression of pancreatic somatostatin receptors in 99mTc-HYNIC-TOC scintigraphy

• Autores: Leticia de la Cueva Barrao, María José Sangrós Sahun, Lina López Vélez, Pablo Navarro Beltrán, Luis Sarría Octavio de Toledo, Mª Soledad Álvarez Ruiz, María Dolores Abós Olivares, P. Lloro
• Localización: Clinical & translational oncology, ISSN 1699-048X, Vol. 19, Nº. 7, 2017, págs. 915-920
• Idioma: inglés
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• Resumen

  • Purpose To describe the frequency of head and/or pancreas uncinate process uptake of 99mTc-HYNIC-TOC, to study its nature, and analyze its diagnostic value.

    Materials and methods Retrospective evaluation of 47 consecutive 99mTc-HYNIC-TOC examinations was conducted. Head and/or pancreas uncinate process uptake was considered to be physiological in patients with normal CT at the same episode and in follow-up. It was analyzed if age or diabetes mellitus was justifying the existence or not of uptake.

    Results 32.5% patients showed uptake; 73% of them were mild. 84.6% patients with uptake have no pathology and 4% had neuroendocrine pancreatic disease at CT. Neither the age nor the diabetes mellitus established differences in patients without lesion.

    Conclusions Near one-third of patients show physiological uptake by head and/or pancreas uncinate process at 99mTc-HYNIC-TOC scintigraphy. It seems that neither the diabetes nor the ages are factors that determine this physiological uptake.