Reactive Arthritis

• Autores: Steven K. Schmitt
• Localización: Infectious disease clinics of North America, ISSN 0891-5520, Vol. 31, Nº. 2, 2017 (Ejemplar dedicado a: Bone and Joint Infections), págs. 265-277
• Idioma: inglés
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• Resumen

  • Reactive arthritis is classified as a spondyloarthropathy. Current concepts of disease suggest an infectious trigger, followed by inflammatory arthritis. Several mechanisms have been proposed to explain the interaction of host susceptibility and microorganism. Diagnosis relies on a compatible clinical syndrome and microbiologic confirmation of the pathogen. Antibiotic therapy seems useful in Chlamydia-triggered arthritis. The role of antibiotics in arthritis triggered by enteric pathogens is less clear. The role of tumor necrosis factor alpha inhibitors in therapy is evolving. Many patients have a course limited to a few months, but others experience extraarticular disease and more prolonged courses.