Small animal imaging: Data that's more than skin deep

• Autores: Jeffrey M. Perkel
• Localización: Science, ISSN 0036-8075, Vol. 348, Nº 6240, 2015, págs. 1271-1273
• Idioma: inglés
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• Resumen

  • To minimize complexity, researchers often study cellular proteins or nucleic acids in isolation. But sometimes—when testing a drug's efficacy and safety, for instance, or monitoring tumor progression—ex vivo just won't do. The only way to know how a compound or cells will behave in the body is to put them into an animal and watch what happens live. The results are easily recognizable in the pages of your favorite journal: the ghostly outline of a mouse, with a telltale multicolored heat bloom indicating where the action is.