Part 4: Targeting Cancer Pathways: The Epigenetics Question

• Autores: Stephen B. Baylin, Charles W.M. Roberts, Ali Shilatifard
• Localización: Science, ISSN 0036-8075, Vol. 349, Nº 6248, 2015, págs. 656-656
• Idioma: inglés
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• Resumen

  • This webinar is the fourth in a series focusing on the cancer pathways that support tumor development, the emerging research in identifying and targeting these pathways, and innovations in the development of increasingly effective cancer therapy options. Recent advances in our understanding of cancer have revealed that the disease cannot be understood through simple analysis of genetic mutations within the cancerous cells. Instead, tumors should be considered as complex tissues in which the cancer cells communicate directly and indirectly with the surrounding cellular microenvironment and evolve traits that promote their own survival. In this webinar we will explore how aberrant changes in epigenetic modification can affect the expression of key genes and contribute to the pathological progression of cancer.