Cyanide

• Autores: Allister Vale
• Localización: Medicine, ISSN-e 1357-3039, Vol. 44, Nº. 3, 2016, págs. 157-157
• Idioma: inglés
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• Resumen

  • Cyanide reversibly inhibits cytochrome oxidase a3. Severe poisoning is characterized by coma, convulsions, cerebral oedema, pulmonary oedema, cardiovascular collapse, cardiac conduction defects, arrhythmias and metabolic acidosis. In addition to oxygen, either dicobalt edetate or hydroxocobalamin should be administered intravenously. If these antidotes are not available, sodium nitrite and sodium thiosulfate should be given.