Serotonin syndrome

• Autores: Ruben Thanacoody
• Localización: Medicine, ISSN-e 1357-3039, Vol. 44, Nº. 2, 2016, págs. 95-96
• Idioma: inglés
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• Resumen

  • The serotonin syndrome is the clinical manifestation of serotonin toxicity in patients taking one or more serotonergic agents. It is characterized by features of neuromuscular hyperactivity, autonomic instability and alteration of mental status. Management consists of discontinuation of the offending drug and supportive care. Cyproheptadine and chlorpromazine, which have 5-hydroxytryptamine type 2A receptor antagonistic properties, may be useful in severe cases.