Sleep-related disorders in Latin-American children with atopic dermatitis:: A case control study

• M. Urrutia-Pereira ^[4] ; R.O.S. Sarni ^[5] ; D. Solé ^[1] ; N.A. Rosario ^[2] ; H.J.C. Neto ^[2] ; V. Acosta ^[6] ; C.F. Almendarez ^[18] ; M.M. Avalos ^[7] ; H. Badellino ^[8] ; F. Berroa ^[9] ; M. Álvarez-Castelló ^[10] ; A.J. Castillo ^[9] ; R.L. Castro-Almarales ^[11] ; M.M. De la Cruz ^[9] ; A.M. Cepeda ^[12] ; C. Fernandez ^[3] ; M. González-León ^[13] ; J. Lozano-Saenz ^[14] ; C. Sanchez-Silot ^[15] ; J.C. Sisul-Alvariza ^[16] ; M. Valentin-Rostan ^[17]
  1. [1] Universidade Federal de São Paulo

     Universidade Federal de São Paulo

     Brasil

     
  2. [2] Universidade Federal do Paraná

     Universidade Federal do Paraná

     Brasil

     
  3. [3] Universidad Nacional del Este

     Universidad Nacional del Este

     Paraguay

     
  4. [4] Unipampa Federal University, Uruguaiana, Rio Grande do Sul, Brazil
  5. [5] ABC Foundation School of Medicine, Brazil
  6. [6] Castelán Pediatric Hospital, Chaco, Argentina
  7. [7] Hospital ISSSTE, Veracruz, Mexico
  8. [8] Clínica Regional del Este, Córdoba, Argentina
  9. [9] Centro de Medicina Avanzada Dr. Abel González, Dominican Republic
  10. [10] Hospital Universitario General Calixto García, Cuba
  11. [11] Centro Nacional de Biopreparados, Havana, Cuba
  12. [12] Hospital Universitario Metropolitano, Barranquilla, Colombia
  13. [13] Centro de Pesquisa: Consultorios del médico de familia, Havana, Cuba
  14. [14] Centro Médico San Angel, Xalapa, Mexico
  15. [15] Hospital Universitario Infantil Sur, Cuba
  16. [16] Clínica de Alergia y Asma, Asuncion, Paraguay
  17. [17] Hospital Pediatrico Pereira Rossell, Montevideo, Uruguay
  18. [18] Centro de Asma y Alergia, Tegucigalpa, Honduras

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• Localización: Allergologia et immunopathologia: International journal for clinical and investigate allergology and clinical immunology, ISSN-e 1578-1267, ISSN 0301-0546, Vol. 45, Nº. 3, 2017, págs. 276-282
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Background Atopic dermatitis (AD) has been associated with impairment of sleep. The aim of this study was to evaluate sleep disorders in AD Latin-American children (4–10 years) from nine countries, and in normal controls (C).

    Methods Parents from 454 C and 340 AD children from referral clinics answered the Children Sleep Habits Questionnaire (CSHQ), a one-week retrospective 33 questions survey under seven items (bedtime resistance, sleep duration, sleep anxiety, night awakening, parasomnias, sleep-disordered breathing and daytime sleepiness). Total CSHQ score and items were analysed in both C and AD groups. Spearman's correlation coefficient between SCORAD (Scoring atopic dermatitis), all subscales and total CSHQ were also obtained.

    Results C and AD groups were similar regarding age, however, significantly higher values for total CSHQ (62.2 ± 16.1 vs 53.3 ± 12.7, respectively) and items were observed among AD children in comparison to C, and they were higher among those with moderate (54.8%) or severe (4.3%) AD. Except for sleep duration (r = −0.02, p = 0.698), there was a significant Spearman's correlation index for bedtime resistance (0.24, p < 0.0001), sleep anxiety (0.29, p < 0.0001), night awakening (0.36, p < 0.0001), parasomnias (0.54, p < 0.0001), sleep-disordered breathing (0.42, p < 0.0001), daytime sleepiness (0.26, p < 0.0001) and total CSHQ (0.46, p < 0.0001). AD patients had significantly higher elevated body mass index.

    Conclusion Latin-American children with AD have sleep disorders despite treatment, and those with moderate to severe forms had marked changes in CSHQ.