Effect of Subcutaneous Dupilumab on Nasal Polyp Burden in Patients With Chronic Sinusitis and Nasal PolyposisA Randomized Clinical Trial

• Autores: Claus Bachert, Leda Mannent, Robert M. Naclerio
• Localización: JAMA: the journal of the American Medical Association, ISSN 0098-7484, Vol. 315, Nº. 5, 2016, págs. 469-479
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • This randomized trial compares the effects of adding dupilumab, an IL-4 and IL-13 signalling inhibitor, to mometasone furoate nasal spray vs mometasone alone in adults with chronic sinusitis and nasal polyposis refractory to intranasal corticosteroids.