Midodrine in refractory chylothorax after pediatric cardiac surgery: A case report

• Autores: Cristina Martínez Roca, María Jesús García Verde, Pedro Yáñez Gómez, Isabel Martín Herranz
• Localización: European journal of clinical pharmacy: atención farmacéutica, ISSN 2385-409X, Vol. 18, Nº. 6, 2016, págs. 414-416
• Idioma: inglés
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• Resumen

  • Chylothorax is a significant complication in pediatric cardiac surgery. The incidence rate is rising due to increased complexity in the patients treated, who often have complex congenital heart diseases. Description of a case of refractory chylothorax in which basic therapeutic strategies, octreotide perfusion and chemical and surgical pleurodesis prove inefficient. In that case, the alpha adrenergic stimulant midodrine was successfully used on a 4-year-old pediatric patient. A dose of 1 mg/8 hours of midodrine was administered for 16 days. We observed a reduction in drainage and an improvement in the nutritional parameters. No adverse effects related to treatment with midodrine were observed. Midodrine could be a therapeutic option in refractory chylothorax in pediatric patients when basic therapeutic management strategies prove inefficient