Impact of Antibiotics on Necrotizing Enterocolitis and Antibiotic-Associated Diarrhea

• Autores: Liza Konnikova, Jeffrey S. Gerber, Michael A. Silverman
• Localización: Gastroenterology clinics of North America, ISSN 0889-8553, Vol. 46, Nº. 1, 2017 (Ejemplar dedicado a: The Gut Microbiome), págs. 61-76
• Idioma: inglés
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• Resumen

  • Antibiotic treatment alters the composition and metabolic function of the intestinal microbiota. These alterations may contribute to the pathogenesis of necrotizing enterocolitis (NEC) and antibiotic-associated diarrhea (AAD). Recent studies are beginning to unravel the contribution of specific groups of microbes and their metabolic pathways to these diseases. Probiotics or other microbiota-targeted therapies may provide effect strategies to prevent and treat NEC and AAD.