Fluoride concentration and pH of pediatric medicines regulary and long-term used by children
- Autores: Isabela Albuquerque Passos, Cláudia Helena Soares de Freitas, Fábio Correia Sampaio
- Localización: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, ISSN-e 1698-6946, Vol. 16, Nº. 3 (Mayo), 2011
- Idioma: inglés
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Resumen
Objectives: Our aim in this study was to determine the fluoride concentration and pH of 71 pediatric medicines regularly and long-term used by children.
Study Design: The fluoride concentration was evaluated by selective electrode of fluoride (Orion). The pH was confronted using specific electrode (Orion) coupled to a potentiometer (Orion). The analyses were accomplished in duplicate. Pearson´s correlation and Kruskal-Wallis test were used. P-values below 5% were considered statistically significant.
Results: Medicine pH averages ± SD varied from 2.3 ±0.01 to up 10.6 ±0.02. Values below critical pH were observed in 42.25% (n=30) of presentations, with 25.35% (n=18) below 4.5 pH. Most medicines (84.5%) presented fluoride concentration below 0.05 mg/L.
Conclusions: Among the pediatric medicines evaluated, this study has showed that 2-4 times-a-day posology and syrup formulations presented lowest pH and fluoride concentration, resulting in factors that predict highest cariogenic and erosive potential.
