Effect of dental restorative materials on total antioxidant capacity and calcium concentration of unstimulated saliva

• Gholam H. Ramezani ^[1] ; Mona-Momeni Moghadam ^[2] ; Mohammad-Ali Saghiri ^[3] ; Franklin Garcia-Godoy ^[4] ; Armen Asatourian ^[5] ; Mohsen Aminsobhani ^[6] ; Mark Scarbecz ^[7] ; Nader Sheibani ^[8]
  1. [1] Islamic Azad University

     Islamic Azad University

     Irán

     
  2. [2] DDS Visiting researcher, Angiogenesis and Regenerative Group, Dr. H. Afsar Lajevardi Research Cluster, Shiraz, Iran
  3. [3] BSc, MSc, PhD, Wisconsin institute for Medical Research and Department of Ophthalmology & Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
  4. [4] DDS, MSc, PhD, Bioscience Research Center, Health Science Center, College of Dentistry, University of Tennessee, Memphis, TN, USA
  5. [5] DDS, Clinical instructor, Angiogenesis and Regenerative Sector, Dr. H. Afsar Lajevardi Research Cluster, Shiraz, Iran
  6. [6] DDS, MSc, Associate professor, Endodontic Department, School of Dentistry, Tehran University of Medical Sciences and AJA University of Medical Sciences, Tehran, Iran
  7. [7] DDS, PhD, Professor, Bioscience Research Center, Health Science Center, College of Dentistry, University of Tennessee, Memphis, TN, USA
  8. [8] BSc, MSc, PhD, Professor, Departments of Ophthalmology & Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA

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• Localización: Journal of Clinical and Experimental Dentistry, ISSN-e 1989-5488, Vol. 9, Nº. 1 (Febrero), 2017, págs. 71-77
• Idioma: inglés
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• Resumen

  • To evaluate the effect of dental amalgam and composite restorations on total antioxidant capacity (TAC) and calcium (Ca) ion concentration of unstimulated saliva.

    Forty-eight children aged 6-10 years selected and divided into three groups of sixteen (8 males, 8 females). In group A and B, samples consisted of two class II dental composite or amalgam restorations, while in group C samples were caries-free (control group). Unstimulated saliva from all samples was collected and TAC was measured by spectrophotometry using an adaptation of 2, 2’-azino-di-(3-ethylbenzthiazoline-6-sulphonate) (ABTS) assay. The Ca ion level was estimated by an auto- analyzer. Data were analyzed with one- and two-way ANOVA test, at a p<.05 level of significance.

    Composite samples showed significantly higher TAC and lower Ca ion levels compared to amalgam and caries-free samples (p<.05). The TAC values showed only significant difference between groups (p<.05), while the Ca ion results showed significant differences within and between groups (p<.05).

    Dental composite restorations increased TAC and decreased Ca ion levels more than amalgam restorations in saliva. Gender is an effective factor in changes induced in oral cavity as females showed more emphatic reaction to dental filling materials than males.

    Patients who have dental restorations, especially dental composites, should pay more attention to their dental hygiene, because dental restorations can increase oxidative stress and decrease Ca ion level in saliva, which might jeopardize remineralization process of tooth structures after demineralization.