CRISPR views of embryos and cells

• Autores: Kai Kupferschmidt
• Localización: Science, ISSN 0036-8075, Vol. 352, Nº 6290, 2016, págs. 1156-1157
• Idioma: inglés
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• Resumen

  • Two teams have developed innovative new applications of the popular genome-editing method CRISPR. One of the groups has used it to mark and trace cells in a developing animal. In the method's first test, described online today in Science, the researchers reveal that many tissues and organs in adult zebrafish form from just a few embryonic cells. Other researchers are already looking to adapt the method to mice, or to exploit it to trace the evolution of tumors. The second group found a way to use CRISPR-guided mutations to record a cell's history—for example, the environmental signals that influence it.