Emerging Technologies for Gut Microbiome Research
- Autores: Jason W. Arnold, Jeffrey Roach, M. Andrea Azcarate-Peril
- Localización: Trends in microbiology, ISSN 0966-842X, Vol. 24, Nº. 11, 2016, págs. 887-901
- Idioma: inglés
- Enlaces
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Resumen
Understanding the importance of the gut microbiome on modulation of host health has become a subject of great interest for researchers across disciplines. As an intrinsically multidisciplinary field, microbiome research has been able to reap the benefits of technological advancements in systems and synthetic biology, biomaterials engineering, and traditional microbiology. Gut microbiome research has been revolutionized by high-throughput sequencing technology, permitting compositional and functional analyses that were previously an unrealistic undertaking. Emerging technologies, including engineered organoids derived from human stem cells, high-throughput culturing, and microfluidics assays allowing for the introduction of novel approaches, will improve the efficiency and quality of microbiome research. Here, we discuss emerging technologies and their potential impact on gut microbiome studies.
