The predictive factors for remission of chronic spontaneous urticaria in childhood: Outcome from a prospective study

• I. Eser ^[1] ; N. Yologlu ^[1] ; C. Baydemir ^[1] ; M. Aydogan ^[1]
  1. [1] University of Kocaeli

     University of Kocaeli

     Turquía

     
• Localización: Allergologia et immunopathologia: International journal for clinical and investigate allergology and clinical immunology, ISSN-e 1578-1267, ISSN 0301-0546, Vol. 44, Nº. 6, 2016, págs. 537-541
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Background There are few studies in children on the natural course of chronic spontaneous urticaria (CSU) because of its relative infrequency in childhood.

    Objective To estimate the rate of remission and evaluate the prognostic factors in children with CSU.

    Method A total of 52 children with CSU were prospectively followed over a period of three years.

    Results The remission rates at 12 months and 36 months were 32.7% and 48.1%. The mean duration of disease at the first visit in the non-remission group was higher than in the remission group at the end of the study (P = 0.016). The remission rate of the patients who had been treated by standard dose antihistamine was higher than that of the patients who had been treated with the high-dose antihistamine and combination medications (P = 0.004, P < 0.001). The treatment steps were independent prognostic factors for remission by logistic regression analysis.

    Conclusion Our study indicates that urticaria controlled by a standard dose of antihistamine can predict a good prognosis independently from disease duration at first visit.